Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Rat HTR7 / 5HT7 Receptor
Rat, Human, Mouse, Dog
Rat HTR7 / 5HT7 Receptor
Rat, Human, Mouse, Dog (tested or 100% immunogen sequence identity)
Protein G purified
Western blot (1 - 2 µg/ml)
IHC - Paraffin
Specificity and Use
HTR7 / 5HT7 Receptor antibody was raised against synthetic peptide from rat HTR7 / 5-HT7.
This sequence is identical for 5-HT7R splice variants in the rat (5-HT7Ra/b/c), human (5-HT7Ra/b/d) and human 5-HT7, the mouse 5-HT7R. It is 93% conserved with dog 5-HT7Ra/b, and 81% conserved with pig 5-HT7R. Recognizes all described 5HT7 receptor splice variants.
5-HT7 Receptor (HTR7 )is a serotonin receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. HTR7 has been implicated in depression, autistic, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa.