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Anti-HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain) IHC-plus™ LS-A2685

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Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
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Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Human, Monkey, Bat, Bovine, Dog, Horse, Pig, Rabbit
IHC - Paraffin
Unconjugated

Details

Human HTR4 / 5-HT4 Receptor
Rabbit
Human, Monkey, Bat, Bovine, Dog, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Mouse, Rat, Hamster (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (15 - 20 µg/ml)

Specificity and Use

HTR4 / 5-HT4 Receptor antibody was raised against synthetic 15 amino acid peptide from 3rd cytoplasmic domain of human 5HT4 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Dog, Bat, Bovine, Rabbit, Horse, Pig (100%); Mouse, Rat, Hamster (93%); Guinea pig, Platypus (87%); Lizard (80%).
LS-E28597 - Liquid - 50 µg - $145.00
Cytoplasmic Domain
Human 5HT4 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About HTR4 / 5-HT4 Receptor

Q13639 NM_000870 NP_000861.1

HTR4 Antibody, 5-HT4 Antibody, 5-HT4R Antibody, 5-HT-4 Antibody, 5HT4 receptor Antibody, 5-HT4 receptor Antibody, 5-hydroxytryptamine 4 receptor Antibody, 5-hydroxytryptamine receptor 4 Antibody, Serotonin 5-HT-4a receptor Antibody, Serotonin receptor 4 Antibody, Cardiac 5-HT4 receptor Antibody, Serotonin 4 receptor Antibody, Serotonin 5-HT-4 receptor Antibody

The 5-HT4 receptor, a member of the Serotonin Receptor subfamily, has been shown to affect the sensory and motor functions of the gut. Some of the most promising emerging therapies in Irritable Bowel Syndrome revolve around targeted pharmacotherapeutic modulation of serotonin receptors (ie, 5-HT3 and 5-HT4 subtypes). At least 9 isoforms (5-HT4A-5-HT4G, and 5-HT4n) have been described, which differ in the length and composition of their intracellular C termini after a common splicing site (L358).

Immunohistochemistry

Immunohistochemistry
Anti-5HT4 Receptor antibody LS-A2685 IHC of human brain, medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry - Paraffin

Immunohistochemistry - Paraffin
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry - Paraffin

Immunohistochemistry - Paraffin
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
 

Requested From: United States
Date Requested: 9/26/2016

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