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| Catalog Number | Size | Price |
|---|---|---|
| LS-B2042-50 | 50 µg (1 mg/ml) | $460 |
1 of 2
2 of 2
IHC‑plus™ Polyclonal Rabbit anti‑Rat HTR3A / 5‑HT3A Receptor Antibody (aa21‑36, IHC, WB) LS‑B2042
IHC‑plus™ Polyclonal Rabbit anti‑Rat HTR3A / 5‑HT3A Receptor Antibody (aa21‑36, IHC, WB) LS‑B2042
Note: This antibody replaces LS-C795, LS-C75763
Antibody:
HTR3A / 5-HT3A Receptor Rabbit anti-Rat Polyclonal (aa21-36) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Rat, Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
HTR3A / 5-HT3A Receptor Rabbit anti-Rat Polyclonal (aa21-36) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Rat, Human
Format:
Unconjugated, Unmodified
Specifications
Description
5-HT3A Receptor antibody LS-B2042 is an unconjugated rabbit polyclonal antibody to 5-HT3A Receptor (HTR3A) (aa21-36) from rat. It is reactive with human and rat. Validated for IHC and WB. Cited in 1 publication.
Target
Rat HTR3A / 5-HT3A Receptor
Synonyms
HTR3A | 5-HT3-A | 5-HT3R-A | 5-HT3 receptor | 5HT3 serotonin receptor | 5-HT3A | 5-HT3a receptor | 5-hydroxytryptamine receptor 3 | 5-HT-3 | 5-HT3 | 5-HT3R | 5HT3R | HTR3 | Serotonin receptor 3A
Host
Rabbit
Reactivity
Rat, Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
This antibody was developed by immunizing rabbits with a mixture of synthetic peptides corresponding to amino acids 21-36 (RATQAHSTTQPALLRL) and 421-436 (LSSIRHSLEKRDEMRE) of rat 5-HT3A receptor, GenBank no AAB02949. Percent identity by BLAST analysis: Rat (100%); Mouse (88%); Hamster (81%).
Epitope
aa21-36
Specificity
In human brain, a 47-50 kD band is observed.
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot (1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B2042 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2042 was determined to be 5 ug/ml.
Presentation
PBS, 0.05% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HTR3A / 5-HT3A Receptor
Validation
Anti-5HT3A receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-5HT3A receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ HTR3A / 5-HT3A Receptor Antibody (aa21-36) for IHC, WB/Western LS-B2042 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (1)
HTR3A is correlated with unfavorable histology and promotes proliferation through ERK phosphorylation in lung adenocarcinoma. Mitsuyo Tone, Shinichiro Tahara, Satoshi Nojima, Daisuke Motooka, Daisuke Okuzaki, Eiichi Morii. Cancer science. 2020 October;111:3953-3961.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot, ELISA
Reactivity:
Human
Range:
0.469-30 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
