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HTR3A / 5-HT3A Receptor
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3A / 5-HT3A Receptor belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Gene Name: | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| Family/Subfamily: | Ion channel , Serotonin 5-HT3 receptor |
| Synonyms: | HTR3A, 5-HT3-A, 5-HT3R-A, 5-HT3 receptor, 5HT3 serotonin receptor, 5-HT3A, 5-HT3a receptor, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3, 5-HT3R, 5HT3R, HTR3, Serotonin receptor 3A |
| Target Sequences: | NM_000869 NP_000860.2 P46098 |
Publications (1)
1
HTR3A is correlated with unfavorable histology and promotes proliferation through ERK phosphorylation in lung adenocarcinoma. Mitsuyo Tone, Shinichiro Tahara, Satoshi Nojima, Daisuke Motooka, Daisuke Okuzaki, Eiichi Morii. Cancer science. 2020 October;111:3953-3961. [Full Text Article]
[PubMed:32736413]
[PMC:PMC7540989]
Related Antibodies: LS-B2042.
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(40)
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HTR3A / 5-HT3A Receptor Rabbit anti-Rat Polyclonal (aa21-36) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
HTR3A / 5-HT3A Receptor Goat anti-Human Polyclonal (aa428-439) Antibody
Human
ICC, IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Bovine, Rat, Chimpanzee, Orangutan, Gibbon, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Bovine, Rat, Chimpanzee, Orangutan, Gibbon, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Dog, Bovine, Rat, Chimpanzee, Orangutan, Gibbon, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
HTR3A / 5-HT3A Receptor Rabbit anti-Rat Polyclonal (aa301-350) Antibody
Rat
WB
Unconjugated
100 µl/$424
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (1st Extracellular Domain) Antibody
Human
ELISA, WB
Unconjugated
40 µg/$485
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
HTR3A / 5-HT3A Receptor Mouse anti-Human Monoclonal (3B11C10) Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µl/$459
HTR3A / 5-HT3A Receptor Mouse anti-Human Monoclonal (4D5E7) Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µl/$459
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (aa30-58) Antibody
Human
WB
Unconjugated
400 µl/$393
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (130-210 aa, Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$431
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (Trp190) Antibody
Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (aa30-58) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (aa30-58) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (aa30-58) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
HTR3A / 5-HT3A Receptor Rabbit anti-Human Polyclonal (aa161-210) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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