Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1F3] (IgG2b) to Human HSPBP1
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Rabbit Polyclonal to Human HSPBP1
Human (tested or 100% immunogen sequence identity)
Specificity and Use
HSPBP1 antibody was raised against truncation mutant that contains amino acids 84-359 of human recombinant HspBP1 (3).
HspBP1 (FL4) is recommended the detection of human HspBP1 by western blotting. The suggested western blotting starting dilution is at 1:1000. Immunoprecipitation and Immunohistochemistry not yet tested.
HSPBP1 Antibody, Hsp70 interacting protein Antibody, Hsp70-binding protein 1 Antibody, Hsp70-interacting protein 1 Antibody, HSPBP Antibody, Hsp70-binding protein 2 Antibody, Hsp70 binding protein 1 Antibody, HspBP2 Antibody, FES1 Antibody, Hsp70-interacting protein 2 Antibody
Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.