Human HSPB1 / HSP27

Mouse

Human, Chimpanzee, Mouse, Rat, Sheep, Chicken (tested or 100% immunogen sequence identity)

IgG1,k Monoclonal

G3.1

Unconjugated

Protein G purified

Unmodified. Also available Azide-free, BSA-free, Ready-to-Use.

Partially purified human HSP27 (earlier called 24K) from breast cancer MCF-7 cells.

Human HSPB1 / HSP27

• IHC
• IHC - Paraffin (0.5 - 1 µg/ml)
• Immunofluorescence (0.5 - 1 µg/ml)
• Western blot (0.25 - 0.5 µg/ml)
• Immunoprecipitation
• Flow Cytometry (0.5 - 1 µg/10E6 cells)
• ELISA

This antibody recognizes a 24-27kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). HSP27 was recently found to be identical to the estrogen-induced [Character 93]p29[Character 94] and [Character 93]24K[Character 94] protein. About 50% of breast carcinomas are positive for HSP27, especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells. ELISA: Order BSA-free format for coating.

1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P04792 NCBI: NM_001540 NP_001531.1