Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey, Mouse, Rat, Bovine, Hamster, Rabbit
IHC - Paraffin, Western blot
Human HSPA8 / HSC70
Human, Monkey, Mouse, Rat, Bovine, Hamster, Rabbit (tested or 100% immunogen sequence identity)
IHC - Paraffin (5 µg/ml)
Western blot (0.5 - 4 µg/ml)
Specificity and Use
HSPA8 / HSC70 antibody was raised against synthetic peptide surrounding amino acid 559 of human Hsc70.
The antibody detects a 71 kD Hsc70. A ~40 kD band can also be detected in human samples. Jurkat cell lysate and mouse small intestine lysate can be used as positive controls. Blocking peptide is also available.
HSPA8 Antibody, Heat shock 70 kDa protein 8 Antibody, Heat shock 70kd protein 10 Antibody, Heat shock 70kD protein 8 Antibody, Heat shock cognate protein 54 Antibody, HSP71 Antibody, HSPA10 Antibody, HSC71 Antibody, HSP73 Antibody, LPS-associated protein 1 Antibody, Heat shock 70kDa protein 8 Antibody, NIP71 Antibody, HSC54 Antibody, HSC70 Antibody, LAP1 Antibody
Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.