Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Protein A purified
IHC - Paraffin (10 µg/ml), Western blot (1:500 - 1:5000), ELISA
Specificity and Use
Synthetic peptide derived from an internal domain of human HSP70
Reacts with a 70 kDa protein. Cross reacts with proteins from many other species due to sequence homology.
Lyophilized from Tris 0.1M, Glycine 0.1M, Sucrose 2%
Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at 4°C. For extended periods store in aliquots at -20°C.
For research use only.
About Heat Shock Protein 70 / HSPA1A
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins.