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HSP90 / Heat Shock Protein 90

Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation. It also stabilizes a number of proteins required for tumor growth, which is why Hsp90 inhibitors are investigated as anti-cancer drugs. Heat shock proteins, as a class, are among the most highly expressed cellular proteins across all species. As their name implies, heat shock proteins protect cells when stressed by elevated temperatures. They account for 1–2% of total protein in unstressed cells. However, when cells are heated, the fraction of heat shock proteins increases to 4–6% of cellular proteins. Heat shock protein 90 (Hsp90) is one of the most common of the heat-related proteins. The "90" comes from the fact that it weighs roughly 90 kiloDaltons. A 90 kDa protein is considered fairly large for a non-fibrous protein. Hsp90 is found in bacteria and all branches of eukarya, but it is apparently absent in archaea. Whereas cytoplasmic Hsp90 is essential for viability under all conditions in eukaryotes, the bacterial homologue HtpG is dispensable under non-heat stress conditions.

HSP90 / Heat Shock Protein 90 Target Details

Target Name: HSP90 / Heat Shock Protein 90
Target Abbreviation: HSP90

Publications (2)

1
Effect of ethanol extracts of Hericium erinaceus mycelium on morphine-induced microglial migration. Chung-Hsin Yeh, Li-Wei Sun, Chang-Mei Lai, Tzu-Pei Yeh, Jong-Ni Lin, Shiow-Luan Tsay, Chin-Chu Chen, Wan-Ping Chen, Chien-Min Chen, Ru-Yin Tsai. Molecular medicine reports. 2019 December;20:5279-5285. [Full Text Article] [PubMed:31638202] Related Antibodies: LS-C380587.
2
Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis. Alexander J Baker-Williams, Fiza Hashmi, Marek A Budzynski, Mark R Woodford, Stephanie Gleicher, Samu V Himanen, Alan M Makedon, Derek Friedman, Stephanie Cortes, Sara Namek, William G Stetler-Stevenson, Gennady Bratslavsky, Alaji Bah, Mehdi Mollapour, Lea Sistonen, Dimitra Bourboulia. Cell reports. 2019 Aug;28:1894-1906.e6. [Full Text Article] [PubMed:31412254] [PMC:PMC8276117]

☰ Filters
Antibodies (99)
ELISA Kits (18)
Proteins (1)
Primary (99)
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Sandwich (15)
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HSP90 / Heat Shock Protein 90 (118)
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Beluga (1)
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C. elegans (2)
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Chlamydomonas reinhardtii (1)
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Drosophila (2)
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Horse (1)
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HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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HSP90 / Heat Shock Protein 90 Rabbit anti-Human Polyclonal (aa250-325) Antibody
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
HSP90 / Heat Shock Protein 90 Antibody - Western blot of Acetyl-HSP 90 (K435) antibody using A459 cells.
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HSP90 / Heat Shock Protein 90 Rabbit anti-Human Polyclonal (acetylation site of K435.) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HSP90 / Heat Shock Protein 90 Antibody - Western blot of Acetyl-HSP 90 (K292/284) antibody
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HSP90 / Heat Shock Protein 90 Rabbit anti-Human Polyclonal (acetylation site of K292/284.) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HSP90 / Heat Shock Protein 90 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,041
HSP90 / Heat Shock Protein 90 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
HSP90 / Heat Shock Protein 90 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
HSP90 / Heat Shock Protein 90 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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HSP90 / Heat Shock Protein 90 Mouse anti-Human Monoclonal (aa1-732) (4F10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
HSP90 / Heat Shock Protein 90 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP90 / Heat Shock Protein 90 Rabbit anti-Human Polyclonal (aa676-693) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human testis, seminiferous ducts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP90 / Heat Shock Protein 90 Mouse anti-Human Monoclonal (4F3.E8) Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human testis, seminiferous ducts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP90 / Heat Shock Protein 90 Mouse anti-Human Monoclonal (Atto 488) (4F3.E8) Antibody
Mouse, Rat, Wheat, Human
ELISA, ICC, IF, IHC, IHC-P, IP, WB
Atto 488 Conjugated
200 µg/$521
HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human testis, seminiferous ducts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP90 / Heat Shock Protein 90 Mouse anti-Human Monoclonal (Atto 594) (4F3.E8) Antibody
Mouse, Rat, Wheat, Human
ELISA, ICC, IF, IHC, IHC-P, IP, WB
Atto 594 Conjugated
200 µg/$521
HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human testis, seminiferous ducts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP90 / Heat Shock Protein 90 Mouse anti-Human Monoclonal (Atto 390) (4F3.E8) Antibody
Mouse, Rat, Wheat, Human
ELISA, ICC, IF, IHC, IHC-P, IP, WB
Atto 390 Conjugated
200 µg/$524
HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human testis, seminiferous ducts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP90 / Heat Shock Protein 90 Mouse anti-Human Monoclonal (APC) (4F3.E8) Antibody
Mouse, Rat, Wheat, Human
ELISA, ICC, IF, IHC, IHC-P, IP, WB
APC Conjugated
200 µg/$521
HSP90 / Heat Shock Protein 90 Antibody - Hsp90 (D7alpha), Human colon carcinoma.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP90 / Heat Shock Protein 90 Mouse anti-Chicken Monoclonal (D7A) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Human
ELISA, IHC, IP, WB
Unconjugated
25 µg/$323; 100 µg/$452
HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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HSP90 / Heat Shock Protein 90 Rabbit anti-Human Polyclonal Antibody
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$485
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HSP90 / Heat Shock Protein 90 Mouse anti-Achlya ambisexualis Monoclonal (PE) (AC88) Antibody
Bacteria, Fish, Mold, Achlya ambisexualis, Beluga, Rat, Hamster, Pig, Rabbit, Mouse, Dog, Guinea pig, Sheep, Scallop, Human, Monkey, C. elegans
Flo
PE Conjugated
50 µg/$418; 200 µg/$677
HSP90 / Heat Shock Protein 90 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
HSP90 / Heat Shock Protein 90 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
HSP90 / Heat Shock Protein 90 Mouse anti-Human Monoclonal (MBH90AB) Antibody
Mouse, Bovine, Human
IHC-P, WB
Unconjugated
0.05 mg/$460
HSP90 / Heat Shock Protein 90 Antibody - Hsp90 complex (8D3) isolation; IP (rabbit reticulocyte lysate) SDS-PAGE Coomassie.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HSP90 / Heat Shock Protein 90 Mouse Monoclonal (8D3) Antibody
Rabbit, Mouse, Rat, Human
IP
Unconjugated
50 µg/$352; 200 µg/$523
HSP90 / Heat Shock Protein 90 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
HSP90 / Heat Shock Protein 90 Antibody - Immunohistochemistry of HSP 90 antibody
Select
HSP90 / Heat Shock Protein 90 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HSP90 / Heat Shock Protein 90 Mouse anti-Human Monoclonal (H9010) Antibody
Chicken, Rabbit, Dog, Rat, Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
HSP90 / Heat Shock Protein 90 Antibody - Anti-HSP90 / Heat Shock Protein 90 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HSP90 / Heat Shock Protein 90 Mouse anti-Achlya ambisexualis Monoclonal (AC-16) Antibody
Chicken, Achlya ambisexualis, Rat, Rabbit, Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
Select
HSP90 / Heat Shock Protein 90 Rat anti-Mouse Monoclonal (2D12) Antibody
Fish, Rat, Mouse, Dog, Bovine, Human
IP, WB
Unconjugated
50 µl/$388; 200 µl/$611
Viewing 1-25 of 118 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).