HSD2 / HSD11B2

hydroxysteroid (11-beta) dehydrogenase 2

There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension.

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Antibodies (45)

Proteins (7)

ELISA Kits (6)

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Custom (2)

Over-Expression Lysate (2)

Primary (45)

Recombinant (5)

Sandwich (4)

Target

HSD2 / HSD11B2 (58)

Reactivity

Human (35)

Mouse (9)

Rat (21)

Bat (3)

Bovine (4)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

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IHC (14)

IHC-P (4)

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Flo (7)

ELISA (15)

ICC (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (44)

mouse (1)

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IHCPlus (1)

Isotype

IgG (34)

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polyclonal pc (45)

Format

96-Well Strip Plate (6)

APC (1)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (5)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

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PE Conjugated (3)

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Epitope

aa58-393 (8)

aa277-306 (7)

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No (58)

Sample Type

Cell Lysates (2)

Plasma (1)

Saliva (1)

Serum (1)

Tissue Homogenates (2)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Rat (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Yeast (1)

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Purified (1)

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Human HSD2 / HSD11B2 Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G22957

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

46.1 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human HSD2 / HSD11B2 (Sandwich ELISA) ELISA Kit - LS-F8771

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Saliva, Tissue Homogenates

Price:

1 Plate/$834

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HSD2 / HSD11B2 Antibody LS-C150690

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

1 Each/$431

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IHC-plus™ HSD2 / HSD11B2 Antibody (aa277-306) LS-B10555

(4.0) Rating

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (aa277-306) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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HSD2 / HSD11B2 Antibody LS-C308319

Antibody:

HSD2 / HSD11B2 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

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HSD2 / HSD11B2 Antibody (aa277-309) LS-C408149

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (aa277-309) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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HSD2 / HSD11B2 Antibody (C-Terminus) LS-C24605

Antibody:

HSD2 / HSD11B2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

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HSD2 / HSD11B2 Antibody (C-Terminus) LS-C24602

Antibody:

HSD2 / HSD11B2 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody

Reactivity:

Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$801

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HSD2 / HSD11B2 Antibody (N-Terminus) LS-C80413

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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HSD2 / HSD11B2 Antibody (aa277-306) LS-C322100

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (aa277-306) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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HSD2 / HSD11B2 Antibody (aa277-306, Biotin) LS-C207123

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (aa277-306) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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HSD2 / HSD11B2 Antibody (aa277-306, FITC) LS-C207125

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (aa277-306) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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HSD2 / HSD11B2 Antibody (aa277-306, PE) LS-C207129

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (aa277-306) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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HSD2 / HSD11B2 Antibody (aa277-306, Azide-free, HRP) LS-C207127

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (aa277-306) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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HSD2 / HSD11B2 Antibody (aa277-306, APC) LS-C207120

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (aa277-306) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• HRP, Azide-free
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • HRP, Azide-free
  • APC

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Human HSD2 / HSD11B2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65308

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.9 kDa

Price:

20 µg/$1,107

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HSD2 / HSD11B2 Antibody LS-C669944

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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HSD2 / HSD11B2 Antibody LS-C490611

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

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HSD2 / HSD11B2 Antibody LS-C666226

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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HSD2 / HSD11B2 Antibody LS-C834503

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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HSD2 / HSD11B2 Antibody LS-C409616

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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HSD2 / HSD11B2 Antibody (C-Terminus) LS-C24606

Antibody:

HSD2 / HSD11B2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$801

Select

HSD2 / HSD11B2 Antibody LS-C403227

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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HSD2 / HSD11B2 Antibody (C-Terminus) LS-C24599

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

Select

HSD2 / HSD11B2 Antibody LS-C779801

Antibody:

HSD2 / HSD11B2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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