Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
HSD17B4 Antibody, 17-beta-HSD IV Antibody, 17-beta-HSD 4 Antibody, Beta-keto-reductase Antibody, D-bifunctional protein Antibody, EDH17B4 Antibody, MPF-2 Antibody, PRLTS1 Antibody, SDR8C1 Antibody, Beta-hydroxyacyl dehydrogenase Antibody, MFE-2 Antibody, Multifunctional protein 2 Antibody
HSD17B4 is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8.
IHC of paraffin-embedded OVCA using HSD17B4 antibody at 1:500 dilution.
HSD17B4 antibody detects HSD17B4 protein at cytoplasm by immunofluorescent analysis. HeLa cells were fixed in 2% paraformaldehyde/culture medium at 37 for 30 min. HSD17B4 protein stained by HSD17B4 antibody diluted at 1:500.
Sample (30 ug of whole cell lysate). A: Hela. 7.5% SDS PAGE. HSD17B4 antibody diluted at 1:1000.
Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. HSD17B4 antibody diluted at 1:1000.