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HSD17B10 / HADH2
hydroxysteroid (17-beta) dehydrogenase 10
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
| Gene Name: | hydroxysteroid (17-beta) dehydrogenase 10 |
| Synonyms: | HSD17B10, 17-beta-HSD 10, 17b-HSD10, CAMR, DUPXp11.22, ABAD, ERAB, HADH2, MHBD, MRPP2, MRX17, SCHAD, SDR5C1, MRX31, MRXS10, Type II HADH, HCD2, XH98G2 |
| Target Sequences: | NM_004493 NP_004484.1 Q99714 |
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HSD17B10 / HADH2 Goat anti-Human Polyclonal (aa242-252) Antibody
Zebrafish, Mouse, Bovine, Rat, Hamster, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
HSD17B10 / HADH2 Mouse anti-Human Monoclonal (OTI11A2) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HSD17B10 / HADH2 Mouse anti-Human Monoclonal (Carrier-free) (OTI11A2) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
HSD17B10 / HADH2 Mouse anti-Human Monoclonal (OTI5E2) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HSD17B10 / HADH2 Mouse anti-Human Monoclonal (Carrier-free) (OTI5E2) Antibody
Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HSD17B10 / HADH2 Mouse anti-Human Monoclonal (OTI10B4) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HSD17B10 / HADH2 Mouse anti-Human Monoclonal (Carrier-free) (OTI10B4) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated
200 µl/$393
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µg/$331
E. coli
His-SUMO
42.8 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
E. coli
His
100 µg/$342; 500 µg/$641; 20 µg/$254
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (aa48-261) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (aa199-235) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (80-160 aa, Internal) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
HSD17B10 / HADH2 Mouse anti-Human Monoclonal (OTI3B5) Antibody
IHC, IHC-P, WB
Unconjugated
100 µl/$434
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$393
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (aa2-261) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (aa2-261) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (aa111-160) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
HSD17B10 / HADH2 Rabbit anti-Human Polyclonal (Glu135) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
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