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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HRH2 / Histamine H2 Receptor Antibody (aa335‑349) LS‑C54969
Note: This antibody replaces LS-C67889
Antibody
Histamine H2 Receptor antibody LS-C54969 is an unconjugated goat polyclonal antibody to Histamine H2 Receptor (HRH2) from human, mouse, rat and other species. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C54969-100
100 µg
Unavailable

Popular HRH2 / Histamine H2 Receptor Products

Anti-HRH2 / Histamine H2 Receptor antibody LS-A1175 IHC of human stomach, parietal cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin
HRH2 antibody (0.1 ug/ml) staining of Duodenum lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Species: Human, Mouse, Rat
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

Histamine H2 Receptor antibody LS-C54969 is an unconjugated goat polyclonal antibody to Histamine H2 Receptor (HRH2) from human, mouse, rat and other species. Validated for Peptide-ELISA and WB.
About HRH2 / Histamine H2 Receptor
The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway. P25021 NM_022304 NP_071640.1

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Specifications

Target
Human HRH2 / Histamine H2 Receptor
Host
Goat
Reactivity
Human, Mouse, Rat, Dog, Horse, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bat, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.3 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:128000)
Failed Applications
  • IHC - Paraffin
Immunogen
Synthetic peptide C-QEEKPLKLQVWSGTE from the C-terminus of human HRH2 / Histamine H2 Receptor (NP_071640.1; NP_001124527.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Horse, Rabbit (100%); Monkey, Hamster, Bat (93%); Guinea pig (87%); Bovine (80%).
Blocking Peptide
LS-E25939 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C54969. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa335-349
Specificity
Human HRH2 / Histamine H2 Receptor. This antibody is expected to recognise both reported isoforms.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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