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HOXC4
homeobox C4
HOXC4 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons.
| Gene Name: | homeobox C4 |
| Synonyms: | HOXC4, Homeobox protein Hox-3E, Homeo box C4, Homeo box 3E, Homeobox protein CP19, Homeobox protein Hox-C4, Cp19, Homeobox C4, HOX3, HOX3E |
| Target Sequences: | NM_014620 NP_055435.2 P09017 |
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