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HOXA9
homeobox A9
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.
| Gene Name: | homeobox A9 |
| Synonyms: | HOXA9, ABD-B, Homeobox protein Hox-A9, HOX1.7, Homeo box A9, Homeobox A9, HOX1, HOX1G, Homeobox protein Hox-1G, Homeodomain protein HOXA9 |
| Target Sequences: | NM_152739 AAB09407.1 P31269 |
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