Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1F12-A6] (IgG1,k) to Human HMOX1 / HO-1
Human, Mouse, Bovine
IHC, ICC, Western blot, Immunoprecipitation, ELISA
Rabbit Polyclonal (IgG) to Rat HMOX1 / HO-1
Rat, Human, Mouse
IHC, Western blot
Rat HMOX1 / HO-1
Rat, Human, Mouse (tested or 100% immunogen sequence identity)
Protein A purified
Specificity and Use
HMOX1 / HO-1 antibody was raised against recombinant rat HO-1 purified from E. coli. The protein contains aa1-261 of rat HO-1 and does not contain the membrane spanning region.
Recognizes purified rat HO-1 and will detect an ~32kD protein, corresponding to the apparent molecular mass of HO-1 (Hsp32) on SDS-PAGE immunoblots, in total lysates and microsome preparations from human, mouse, rat, canine, guinea pig, hamster, monkey and rabbit.
Suitable for use in Western Blot and Immunohistochemistry. Western Blot (ECL): 1:1000.
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.