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Anti-HMBS / PBGD Antibody (clone 3E8) LS-C197420

Catalog Size Price
LS-C197420-100 100 µg Unavailable

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100% Guaranteed
Mouse Monoclonal [clone 3E8] (IgG2a,k) to Human HMBS / PBGD
Western blot, ELISA


Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [3E8]
Purified from ascites by Protein A


  • Western blot

Specificity and Use

HMBS / PBGD antibody was raised against hMBS (AAH00520.1, aa1-361 full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sandwich ELISA: Recombinant protein. Western Blot: Transfected lysate, Recombinant protein.


PBS, pH 7.4
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
For research use only.


P08397 NM_000190 NP_000181.2

HMBS Antibody, Hydroxymethylbilane synthase Antibody, PBG-D Antibody, PBGD Antibody, PORC Antibody, Porphyria, acute Chester type Antibody, Porphobilinogen deaminase Antibody, Pre-uroporphyrinogen synthase Antibody, UPS Antibody, Uroporphyrinogen I synthetase Antibody, Uroporphyrinogen I synthase Antibody

HMBS / PBGD is a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Western blot

Western blot
Western Blot analysis of HMBS expression in transfected 293T cell line by HMBS monoclonal antibody (M01), clone 3E8.Lane 1: HMBS transfected lysate(39.71 KDa).Lane 2: Non-transfected lysate.

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged HMBS is approximately 1 ng/ml as a capture antibody.

Requested From: 
Date Requested: 3/23/2018

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