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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HM13 / IMP‑1 / SPP Antibody (aa325‑354) LS‑C164926
SPP antibody LS-C164926 is an unconjugated rabbit polyclonal antibody to human SPP (HM13 / IMP-1). Validated for WB.
Catalog
Size
Price
LS-C164926-400
400 µl
Unavailable

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Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

SPP antibody LS-C164926 is an unconjugated rabbit polyclonal antibody to human SPP (HM13 / IMP-1). Validated for WB.
About HM13 / IMP-1 / SPP
Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. May play a role in graft rejection (By similarity). Q8TCT9 NM_030789 NP_110416.1

HM13 Antibody, DJ324O17.1 Antibody, HIMP1 Antibody, IMP1 Antibody, Intramembrane protease 1 Antibody, H13 Antibody, MSTP086 Antibody, IMP-1 Antibody, IMPAS Antibody, IMPAS-1 Antibody, Presenilin-like protein 3 Antibody, PSL3 Antibody, Signal peptide peptidase Antibody, Signal peptide peptidase beta Antibody, SPP Antibody, PSENL3 Antibody, SPPL1 Antibody


Specifications

Target
Human HM13 / IMP-1 / SPP
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E3244 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C164926. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa325-354
Specificity
This HM13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of human HM13.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

HM13 Antibody western blot of HeLa cell line lysates (35 ug/lane). The HM13 antibody detected the HM13 protein (arrow).
HM13 Antibody western blot of HeLa cell line lysates (35 ug/lane). The HM13 antibody detected the HM13 protein (arrow).

Western blot

HM13 Antibody western blot of HeLa cell line lysates (35 ug/lane). The HM13 antibody detected the HM13 protein (arrow).
HM13 Antibody western blot of HeLa cell line lysates (35 ug/lane). The HM13 antibody detected the HM13 protein (arrow).

Western blot

HM13 Antibody western blot of HeLa cell line lysates (35 ug/lane). The HM13 antibody detected the HM13 protein (arrow).
HM13 Antibody western blot of HeLa cell line lysates (35 ug/lane). The HM13 antibody detected the HM13 protein (arrow).

Western blot

HM13 Antibody western blot of HeLa cell line lysates (35 ug/lane). The HM13 antibody detected the HM13 protein (arrow).
HM13 Antibody western blot of HeLa cell line lysates (35 ug/lane). The HM13 antibody detected the HM13 protein (arrow).


Requested From: 
Date Requested: 6/18/2018

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