Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Specificity and Use
HLA-DR4 antibody was raised against hLA Class 2 Antigen-DR4.
Recognizes HLA Class 2 Antigen-DR4. Additional cross-reactivity occurs with related proteins +0401, +0403,+/- DR1, -/+0402, -/+ DR7 Specificity was determined at a 1:10 dilution by the microcytotoxicity test under standard NIH conditions. Note that 30% of DR17 (DR3) reacted with false positivity using this antibody.
Suitable for use in microcytotoxicity studies.
Lyophilized, PBS, 1% BSA.
100 µl Sterile dH20
Store at -20°C prior to reconstitution. After reconstitution aliquot and freeze at-20°C. Avoid frequent freeze thaws.