LSBio The Immunohistochemistry Antibody Company
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-HLA-DR Antibody (clone L243, Azide-free, Low Endotoxin) LS-C101324

Note: This antibody replaces LS-C204379


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $205
500 µg - 1 mg/ml $315
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Related Products

Most Popular HLA-DR Antibodies

Anti-HLA-DR Antibody (clone L243) LS-C41093
Mouse Monoclonal [clone L243] (IgG2a) to Human HLA-DR
Human, Baboon, Monkey, Dog
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Flow Cytometry Image
Anti-HLA-DR Antibody (clone YE2/36 HLK) IHC-plus™ LS-B7229
Rat Monoclonal [clone YE2/36 HLK] (IgG2a) to Human HLA-DR
IHC - Paraffin, IHC - Frozen, Flow Cytometry
Immunohistochemistry Image
Anti-HLA-DR Antibody (clone 423L, PE) LS-C140404
Mouse Monoclonal [clone 423L] (IgG2a) to Human HLA-DR
Flow Cytometry
PE Conjugated

100% Guaranteed 100% Guaranteed Publications Publications (4)
Mouse Monoclonal [clone L243] (IgG2a,k) to Human HLA-DR
Human, Baboon, Monkey, Dog
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, Blocking
Unconjugated, Azide-free, Low Endotoxin


Human HLA-DR
Human, Baboon, Monkey, Dog (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [L243]
Immunoaffinity purified
Azide-free, Low Endotoxin


  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry
  • Blocking

Specificity and Use

For immunofluorescent staining, the suggested use of this reagent is = 0.5 µg per 106 cells in 100 µl volume or 100 µl whole blood. It is recommended that the reagent be titrated for optimal performance for each application. IHC-Fr was performed using acetone-fixed sections.


Phosphate-buffered solution, pH 7.2, containing no preservative. 0.2 µm filter sterilized. Endotoxin level is < 0.1 EU/µg of the protein (< 0.01 ng/µg of the protein) as determined by the LAL test.
Store undiluted at +4C. This antibody contains no preservative; handle under aseptic conditions.
For research use only.

Publications (4)

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. Zaba LC, Cardinale I, Gilleaudeau P, Sullivan-Whalen M, Surez-Farias M, Surez Farias M, Fuentes-Duculan J, Novitskaya I, Khatcherian A, Bluth MJ, Lowes MA, Krueger JG. The Journal of experimental medicine. 2007 204:3183-94. [PubMed:18039949] [PMC:PMC2150965]
Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production. Fujita H, Nograles KE, Kikuchi T, Gonzalez J, Carucci JA, Krueger JG. Proceedings of the National Academy of Sciences of the United States of America. 2009 106:21795-800. [PubMed:19996179] [PMC:PMC2799849]
Basophils and the T helper 2 environment can promote the development of lupus nephritis. Charles N, Hardwick D, Daugas E, Illei GG, Rivera J. Nature medicine. 2010 16:701-7. [PubMed:20512127] [PMC:PMC2909583]
CD4+ CD25+ Foxp3+ regulatory T cells, dendritic cells, and circulating cytokines in uncomplicated malaria: do different parasite species elicit similar host responses?. Gonalves RM, Salmazi KC, Santos BA, Bastos MS, Rocha SC, Boscardin SB, Silber AM, Kalls EG, Ferreira MU, Scopel KK. Infection and immunity. 2010 78:4763-72. [PubMed:20713627] [PMC:PMC2976362]

About HLA-DR

HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR and its ligand, a peptide of 9 amino acids in length or longer, constitutes a ligand for the T-cell receptor (TCR). HLA (human leukocyte antigens) were originally defined as cell surface antigens that mediate graft-versus-host disease, which resulted in the rejection of tissue transplants in HLA-mismatched donors.

Flow Cytometry

Flow Cytometry
Human peripheral blood lymphocytes stained with LEAF purified L243, followed by anti-mouse IgG FITC

Requested From: United States
Date Requested: 10/25/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number