Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
HLA-DQA1 Antibody, DC-alpha Antibody, DQ-A1 Antibody, DC-1 alpha chain Antibody, Leukocyte antigen alpha chain Antibody, GSE Antibody, MHC class II DQA1 Antibody, HLA-DCA Antibody, HLA-DQA Antibody, MHC class II antigen Antibody, CELIAC1 Antibody, Leucocyte antigen DQA1 Antibody, MHC class II HLA-DQ-alpha-1 Antibody, MHC HLA-DQ alpha Antibody
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa.
Western blot of HLA-DQA1 (arrow) using rabbit polyclonal HLA-DQA1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HLA-DQA1 gene.
HLA-DQA1 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The HLA-DQA1 antibody detected the HLA-DQA1 protein (arrow).
HLA-DQA1 Antibody flow cytometry of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.