Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
HLA-DQA1 Antibody, DC-alpha Antibody, DQ-A1 Antibody, DC-1 alpha chain Antibody, Leukocyte antigen alpha chain Antibody, GSE Antibody, MHC class II DQA1 Antibody, HLA-DCA Antibody, HLA-DQA Antibody, MHC class II antigen Antibody, CELIAC1 Antibody, Leucocyte antigen DQA1 Antibody, MHC class II HLA-DQ-alpha-1 Antibody, MHC HLA-DQ alpha Antibody
Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.
Western blot of HLA-DQA1 (arrow) using rabbit polyclonal HLA-DQA1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HLA-DQA1 gene.
HLA-DQA1 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The HLA-DQA1 antibody detected the HLA-DQA1 protein (arrow).
HLA-DQA1 Antibody flow cytometry of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Requested From: United States
Date Requested: 2/10/2016