Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone WR18] (IgG2a) to Human HLA-DP+DQ+DR
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [WR18]
Flow Cytometry (1:1 - 1:10)
Specificity and Use
Recognizes a common determinant on the beta chain of human MHC Class II, and stains cells expressing HLA-DR, DP and DQ. The antigen is expressed by B lymphocytes, monocytes and activated T lymphocytes.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. Method sheets are available on request.
PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.