Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone Bu26] (IgG1) to Human HLA-DP+DQ+DR
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [Bu26]
Flow Cytometry (1:100 - 1:200)
Specificity and Use
Recognizes the beta chains of class II human major histocompatibility (MHC) antigens. The Reacts with DP, DQ, DR beta chains, which are expressed by antigen presenting cells, B- cells, monocytes and activated T lymphocytes. MHC class II molecules play a central role in the immune system by presenting peptides derived from extracellular proteins.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.
PBS, pH 7.4, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.