HLA-C

Major Histocompatibility Complex, Class I, C heavy chain

HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described

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Products

Antibodies (31)

Proteins (4)

ELISA Kits (3)

Type

Primary (31)

Recombinant (4)

Sandwich (2)

Sandwich CLIA (1)

Target

HLA-C (38)

Reactivity

Human (34)

Mouse (3)

Rat (2)

Chimpanzee (4)

Dog (3)

Orangutan (3)

Pig (8)

Application

IHC (4)

IHC-P (2)

WB (30)

ELISA (11)

ICC (3)

IP (2)

Host

rabbit (30)

mouse (1)

Isotype

IgG (16)

Clonality

polyclonal pc (31)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (1)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (13)

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Epitope

aa48-305 (8)

aa66-93 (7)

aa208-257 (4)

aa38-62 (1)

Publications

No (38)

Sample Type

Plasma (3)

Serum (3)

Tissue Homogenates (1)

Tag

6His, N-terminus (1)

GST (1)

His (1)

His, N-terminus (1)

Species

Human (4)

Source

E. coli (3)

Wheat Germ Extract (1)

Purification

Purified (2)

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HLA-C Antibody LS-C285744

Antibody:

HLA-C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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HLA-C Antibody (HRP) LS-C316743

Antibody:

HLA-C Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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HLA-C Antibody (Biotin) LS-C316741

Antibody:

HLA-C Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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HLA-C Antibody (FITC) LS-C316742

Antibody:

HLA-C Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Human HLA-C (Sandwich ELISA) ELISA Kit - LS-F22179

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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HLA-C Antibody (aa38-62) LS-C357562

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa38-62) Antibody

Reactivity:

Mouse, Rat, Chimpanzee, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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HLA-C Antibody (aa48-305) LS-C374325

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa48-305) Antibody

Reactivity:

Pig, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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HLA-C Antibody (aa48-305, HRP) LS-C711027

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa48-305) (HRP) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

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HLA-C Antibody (aa48-305, Biotin) LS-C686741

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa48-305) (Biotin) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

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HLA-C Antibody (aa48-305, Cy3) LS-C702000

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa48-305) (Cy3) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• HRP
• Biotin
• Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • Cy3

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HLA-C Antibody LS-C490057

Antibody:

HLA-C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

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Human HLA-C Protein (Recombinant His, N-terminus) (aa48-305) - LS-G24636

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

33.2kDa

Price:

10 µg/$299; 50 µg/$552; 100 µg/$882; 200 µg/$1,080; 1 mg/$2,261; 500 µg/$1,775; 5 mg/$3,851; 2 mg/$2,453

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HLA-C Antibody LS-C408279

Antibody:

HLA-C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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HLA-C Antibody LS-C830045

Antibody:

HLA-C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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HLA-C Antibody (aa66-93) LS-C321987

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa66-93) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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HLA-C Antibody (aa66-93, Biotin) LS-C215099

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa66-93) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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HLA-C Antibody (aa66-93, FITC) LS-C215098

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa66-93) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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HLA-C Antibody (aa66-93, APC) LS-C215096

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa66-93) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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HLA-C Antibody (aa66-93, Azide-free, HRP) LS-C215100

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa66-93) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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HLA-C Antibody (aa66-93, PE) LS-C215101

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa66-93) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

HLA-C Antibody LS-C311213

Antibody:

HLA-C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$749

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HLA-C Antibody LS-C155124

Antibody:

HLA-C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$402

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HLA-C Antibody (aa208-257) LS-C146237

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa208-257) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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HLA-C Antibody (aa66-93) LS-C159842

Antibody:

HLA-C Rabbit anti-Human Polyclonal (aa66-93) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

HLA-C Antibody LS-C668623

Antibody:

HLA-C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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