Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone BB7.1] (IgG1) to Human HLA-B7
Human, Cynomolgus monkey
Flow Cytometry (applications tested for the base form of this product only)
Human, Cynomolgus monkey (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [BB7.1]
Also available conjugated with FITC, RPE.
Flow Cytometry (1:50)
(applications tested for the base form of this product only)
Specificity and Use
HLA-B7 antibody was raised against papain solubilized HLA-B7 antigen.
Recognizes the HLA-B7 antigen and does not cross-react with HLA-B27 or other related antigens. It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (i. e. HLA-B7 positive) in the investigation of diseases such as ankylosing spondylitis and anterior uveitis.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells or 100 ul whole blood. Method sheets are available on request.
Staining of human peripheral blood lymphocytes from an HLA-B7 positive donor with mouse anti human HLA-B7. This image was taken for the unconjugated form of this product. Other forms have not been tested.