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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HLA‑B Antibody LS‑C24468
HLA-B antibody LS-C24468 is an unconjugated mouse monoclonal antibody to HLA-B from human and monkey. Validated for Flow.
Antibody
Catalog
Size
Price
LS-C24468-200
200 µg
Unavailable

Popular HLA-B Products

Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Human
Applications: Cytotoxic Assay
Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Human
Applications: IHC, IHC - Frozen, Western blot

Product Description

HLA-B antibody LS-C24468 is an unconjugated mouse monoclonal antibody to HLA-B from human and monkey. Validated for Flow.
About HLA-B
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. P01889 NM_005514 NP_005505.2

HLA-B Antibody, HLAB Antibody, MHC Class I HLA heavy chain Antibody, Leukocyte antigen class I-B Antibody, SPDA1 Antibody


Specifications

Target
Human HLA-B
Host
Mouse
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, Biotin, HRP.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Flow Cytometry (1:25)
  • (applications tested for the base form of this product only)
Immunogen
HLA-B antibody was raised against papain solubilized HLA-B7 antigen.
Specificity
Recognizes human HLA-B7 antigen. Does not cross-react with HLA-B27 or other related antigens. Distinguishes true HLA-B27 positives from false HLA-B27 positives (i. e. HLA-B7 positive) in the investigation of diseases such as ankylosing spondylitis and anterior uveitis. Species cross-reactivity: Cynomolgus monkey.
Usage
Suitable for use in Flow Cytometry. Flow Cytometry: 1:25. Use 20 ul to label 1x1E6 cells or 100 ul whole blood.
Presentation
PBS, pH 7.4, 0.09% sodium azide, 40% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/19/2018

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