Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
HLA-A Antibody, Leukocyte antigen class I-A Antibody, HLAA Antibody, HLA class I histocompatibility antigen, A-1 alpha chain Antibody
HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons.
Western Blot analysis of HLA-A expression in transfected 293T cell line by HLA-A monoclonal antibody (M01), clone 2D6.Lane 1: HLA-A transfected lysate (Predicted MW: 40.8 KDa).Lane 2: Non-transfected lysate.
HLA-A monoclonal antibody (M01), clone 2D6. Western Blot analysis of HLA-A expression in A-431.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged HLA-A is 3 ng/ml as a capture antibody.
Requested From: United States
Date Requested: 1/24/2017