Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [IPO-M6]
IHC - Paraffin
IHC - Frozen
Specificity and Use
HL-60 Leukemia antibody was raised against iPO-M6 was generated after immunization of a BALB/c mouse with human cell line HL-60. Mouse splenocytes were fused with the mouse myeloma cell line P3-X63-Ag8.653.
IPO-M6 reacts with human leukemia cell line HL-60 and immuno-precipitates with two proteins with MW of 48 and 52 kD. IPO-M6 does not stain B cell lines Daudi, PHS, Namalwa, RPMI1788 and T-cell lines CCRF-HSB2, Jurkat and Molt-4.