Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Mouse Monoclonal (IgM) to Rat HK1 / Hexokinase 1
Rat HK1 / Hexokinase 1
Rat (tested or 100% immunogen sequence identity)
Western blot (1:100 - 1:500)
Specificity and Use
Rat Type I hexokinase.
Recognizes a segmental epitope located in the C-terminal half of the Type I hexokinase sequence.
Suitable for use in Western Blot. Western Blot: 1:100-1:500. Note: This antibody is recommended only for use on pure enzyme. It is useful for identifying specific fragments of the Type I hexokinase as, for example, generated by proteolysis or expression from truncated cDNAs. It is not recommend for use on crude tissue extracts.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C.
HK1 Antibody, Brain form hexokinase Antibody, Hexokinase 1 Antibody, Hexokinase type I Antibody, HK I Antibody, HK1-tb Antibody, HK1-tc Antibody, HKI Antibody, Hexokinase type 1 Antibody, HK1-ta Antibody, HXK1 Antibody, Glycolytic enzyme Antibody, Hexokinase-1 Antibody, Type 1 hexokinase Antibody, Type i hexokinase Antibody
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific.