Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Goat Polyclonal (IgG) to Human Immunodeficiency Virus HIV-1 gp41
Human Immunodeficiency Virus, Human, Virus
Western blot, ELISA
Human Immunodeficiency Virus HIV-1 gp41
Human Immunodeficiency Virus, Human, Virus (tested or 100% immunogen sequence identity)
Western blot (1:2000)
Specificity and Use
HIV-1 gp41 antibody was raised against recombinant HIV1 gp41 antigen.
Reacts strongly with Immunodeficiency Virus 1 gp41, gp120 and gp160 in western blot assays. ELISA based peptide mapping studies have confirmed high titer reactivity to HIV MN env peptide in the following regions: (6332)IEPLGVAPTKAKRRV, (6360)CTTTVPWNASWSNKS and moderate activity to multiple other regions on the env polypeptide. The viral envelope protein gp160 is cleaved into fragments gp120 and gp41. gp120 is an exterior envelope glycoprotein on the surface of the virus particle that binds to CD4 and chemokine receptors on macrophages and T-lymphocytes. gp41 is non-covalently bound to gp120 and aids the virus in entering the cell.
150mM sodium chloride, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.