HIV-1 env

HIV-1 gp160

The surface protein gp120 (SU) attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. This peculiar 2 stage receptor-interaction strategy allows gp120 to maintain the highly conserved coreceptor-binding site in a cryptic conformation, protected from neutralizing antibodies. Since CD4 also displays a binding site for the disulfide-isomerase P4HB/PDI, a P4HB/PDI-CD4-CXCR4-gp120 complex may form. In that complex, P4HB/PDI could reach and reduce gp120 disulfide bonds, causing major conformational changes in gp120. TXN, another PDI family member could also be involved in disulfide rearrangements in Env during fusion. These changes are transmitted to the transmembrane protein gp41 and are thought to activate its fusogenic potential by unmasking its fusion peptide.

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Products

Antibodies (41)

Proteins (2)

Type

Primary (41)

Recombinant (2)

Target

HIV-1 env (43)

Reactivity

Human (5)

Human Immunodeficiency Virus (29)

Human Immunodeficiency Virus 1 (7)

Human Immunodeficiency Virus 2 (5)

Application

IHC (4)

IHC-Fr (1)

WB (37)

Flo (1)

ELISA (35)

ICC (5)

IF (4)

IP (2)

Host

rabbit (8)

mouse (22)

goat (11)

Product Group

Retroviridae (41)

Isotype

IgG (24)

IgG1 (7)

IgG2a (8)

IgG2b (1)

Clonality

monoclonal mc (22)

polyclonal pc (19)

Format

APC Conjugated (2)

Biotin Conjugated (6)

FITC Conjugated (5)

Gold Conjugated (1)

HRP Conjugated (6)

PE Conjugated (2)

Unconjugated (19)

Epitope

aa39-517 (1)

aa390-702 (1)

aa730-750 (1)

Publications

No (43)

Tag

His,C-terminus (2)

Species

Human Immunodeficiency Virus (2)

Source

Human Embryonic Kidney 293 Cells (2)

Low Endotoxin Level

Low endotoxin level (2)

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HIV-1 env Antibody (Biotin) LS-C36726

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal (Biotin) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, Flo, ICC, WB

Format:

Biotin Conjugated

Price:

50 µg/$778

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HIV-1 env Antibody LS-C123770

Antibody:

HIV-1 env Goat anti-Human Immunodeficiency Virus Polyclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

1 ml/$694

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HIV-1 env Antibody LS-C36729

Antibody:

HIV-1 env Rabbit anti-Human Immunodeficiency Virus Polyclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$772

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HIV-1 env Antibody (aa730-750) LS-C36756

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal (aa730-750) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, ICC, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$655

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HIV-1 env Antibody (Biotin) LS-C36748

Antibody:

HIV-1 env Goat anti-Human Immunodeficiency Virus Polyclonal (Biotin) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, ICC, IF, WB

Format:

Biotin Conjugated

Price:

1 ml/$548

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HIV-1 env Antibody LS-C36793

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$832

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HIV-1 env Antibody LS-C415679

Antibody:

HIV-1 env Rabbit anti-Human Immunodeficiency Virus 1 Polyclonal Antibody

Reactivity:

Human Immunodeficiency Virus 1

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$432

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HIV-1 env Antibody LS-C36684

Antibody:

HIV-1 env Goat anti-Human Immunodeficiency Virus Polyclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, ICC, WB

Format:

Unconjugated

Price:

1 ml/$562

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HIV-1 env Antibody LS-C36681

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

IF, WB

Format:

Unconjugated

Price:

1 ml/$611

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HIV-1 env Antibody (aa39-517) LS-C36685

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal (aa39-517) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$842

Select

HIV-1 env Antibody (HRP) LS-C36747

Antibody:

HIV-1 env Goat anti-Human Immunodeficiency Virus Polyclonal (HRP) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, ICC, WB

Format:

HRP Conjugated

Price:

1 ml/$587

Select

HIV-1 env Antibody LS-C36719

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$655

Select

HIV-1 env Antibody LS-C36801

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$842

Select

HIV-1 env Antibody (aa390-702) LS-C36796

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal (aa390-702) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$740; 1 mg/$1,154

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HIV-1 env Antibody (APC) LS-C517339

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus 2 Monoclonal (APC) Antibody

Reactivity:

Human, Human Immunodeficiency Virus 2

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$1,001

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HIV-1 env Antibody (PE) LS-C654900

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus 2 Monoclonal (PE) Antibody

Reactivity:

Human, Human Immunodeficiency Virus 2

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$1,001

• Unconjugated
• APC
• PE

• Unconjugated
• APC
• PE

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HIV-1 env Antibody LS-C36797

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$842

Select

HIV-1 env Antibody (FITC) LS-C36727

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal (FITC) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

IF, WB

Format:

FITC Conjugated

Price:

50 Tests/$649

Select

HIV-1 env Antibody (Gold) LS-C36728

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal (Gold) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

IHC, WB

Format:

Gold Conjugated

Price:

1 ml/$1,094

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HIV-1 env Antibody LS-C669007

Antibody:

HIV-1 env Rabbit anti-Human Immunodeficiency Virus 1 Polyclonal Antibody

Reactivity:

Human Immunodeficiency Virus 1

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$460

Select

HIV-1 env Antibody LS-C36746

Antibody:

HIV-1 env Goat anti-Human Immunodeficiency Virus Polyclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

1 ml/$562

Select

HIV-1 env Antibody LS-C36741

Antibody:

HIV-1 env Goat anti-Human Immunodeficiency Virus Polyclonal Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

1 mg/$665

Select

HIV-1 env Antibody (HRP) LS-C36720

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal (HRP) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

200 Tests/$717

Select

HIV-1 env Antibody (Biotin) LS-C36721

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal (Biotin) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

50 µg/$778

Select

HIV-1 env Antibody (HRP) LS-C36725

Antibody:

HIV-1 env Mouse anti-Human Immunodeficiency Virus Monoclonal (HRP) Antibody

Reactivity:

Human Immunodeficiency Virus

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

200 Tests/$637

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