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Anti-HIV-1 env Antibody (FITC) LS-C36722

Catalog Size Price
LS-C36722-50 50 tst Unavailable

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100% Guaranteed
Mouse Monoclonal (IgG) to Human Immunodeficiency Virus HIV-1 env
Human Immunodeficiency Virus
Western blot
FITC Conjugated

Details

Human Immunodeficiency Virus HIV-1 env
Mouse
Human Immunodeficiency Virus (tested or 100% immunogen sequence identity)
IgG Monoclonal
Fluorescein
Purified
Unmodified

Applications

Western blot

Specificity and Use

Binds to native and recombinant HIV-1 gp120 in Dot Blot assays and stains cell surfaces in direct immunofluorescence assays.
Direct Immunofluorescent staining of cells may be performed in 1:50 dilution range. Dot Blot assays with purified gp120 may be performed in 1:200 dilution range. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

10 mM Tris, pH 8.0. No stabilizers or preservatives added.
For research use only.

About HIV-1 env

P04578 P04578

env Antibody, HIV-1 Envelope Glycoprotein Antibody

The surface protein gp120 (SU) attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. This peculiar 2 stage receptor-interaction strategy allows gp120 to maintain the highly conserved coreceptor-binding site in a cryptic conformation, protected from neutralizing antibodies.

Requested From: 
Date Requested: 10/23/2017

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