Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Leech (tested or 100% immunogen sequence identity)
Specificity and Use
Hirudin antibody was raised against purified recombinant full-length hirudin coupled to carrier protein.
No reaction was obtained with human plasma or serum when analyzed by immunoelectrophoresis. Reactivity to hirudin was demonstrated by ELISA. Prior to conjugation to peroxidase, IgG demonstrated ability to inhibit the anticoagulant activity of hirudin in plasma, but not the activities of the analogues hirugen and hirulog. Preparation may also contain reactivity to keyhole limpet hemocyanin (KLH) which was used as a non-mammalian carrier protein.
Suitable for use as a source of peroxidase-labeled antibodies to hirudin. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Supplied in a buffered stabilizer solution, 50% glycerol.