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HINT / HINT1

histidine triad nucleotide binding protein 1

Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

Gene Name: histidine triad nucleotide binding protein 1
Synonyms: HINT1, HINT, NMAN, Protein kinase C inhibitor 1, PKCI-1, PKCI1, PRKCNH1
Target Sequences: NM_005340 NP_005331.1 P49773

☰ Filters
Antibodies (31)
Proteins (7)
ELISA Kits (3)
Cell-Based (1)
Over-Expression Lysate (2)
Primary (31)
Recombinant (5)
Sandwich (2)
HINT / HINT1 (41)
Human (32)
Mouse (23)
Rat (22)
Bovine (6)
Chicken (6)
Chimpanzee (6)
Dog (6)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (6)
Orangutan (6)
Pig (6)
Rabbit (6)
Xenopus (3)
Zebrafish (3)
IHC (18)
IHC-P (14)
WB (26)
Flo (1)
ELISA (8)
ICC (1)
IF (7)
IP (2)
Peptide-ELISA (4)
rabbit (29)
mouse (2)
Product Group
IHCPlus (5)
IgG (25)
IgG1,k (1)
IgG2b,k (1)
monoclonal mc (2)
polyclonal pc (29)
1500CT836.13.93 (1)
2D7 (1)
96-Well Microplate (1)
96-Well Strip Plate (2)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (22)
N-Terminus (4)
aa38-87 (4)
40-120 aa, Internal (1)
Asn99 (1)
aa1-50 (1)
aa50-99 (1)
aa59-92 (1)
aa71-120 (1)
aa76-126 (1)
No (41)
Adherent Cell Cultures (1)
Cell Culture Supernatants (1)
Cell Lysates (2)
Tissue Homogenates (2)
10His, N-terminus + Myc, C-terminus (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (5)
Rabbit (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (3)
HINT / HINT1 Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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HINT / HINT1 Mouse anti-Human Monoclonal (1500CT836.13.93) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
200 µl/$460
HINT / HINT1 Antibody - HINT1 antibody IHC-paraffin. IHC(P): Mouse Intestine Tissue.
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HINT / HINT1 Rabbit anti-Human Polyclonal (aa59-92) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
HINT / HINT1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
HINT / HINT1 Mouse anti-Human Monoclonal (2D7) Antibody
Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$460
HINT / HINT1 Antibody - Anti-HINT1 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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HINT / HINT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
HINT / HINT1 Antibody - Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
HINT / HINT1 Antibody - Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Bovine, Rat, Pig, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
HINT / HINT1 Antibody - Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Bovine, Rat, Pig, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
HINT / HINT1 Antibody - Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Bovine, Rat, Pig, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
HINT / HINT1 Antibody - Immunohistochemistry image of paraffin-embedded human testis tissue at a dilution of 1:100
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HINT / HINT1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (40-120 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HINT / HINT1 Antibody - Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (aa38-87) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
HINT / HINT1 Antibody - Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (aa38-87) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
HINT / HINT1 Antibody - Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (aa38-87) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
HINT / HINT1 Antibody - Anti-HINT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (aa38-87) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
Select
HINT / HINT1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
HINT / HINT1 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using HINT1 Polyclonal Antibody at dilution of 1:30.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HINT / HINT1 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using HINT1 Polyclonal Antibody at dilution of 1:50.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HINT / HINT1 Antibody
Select
HINT / HINT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
HINT / HINT1 Antibody - Peptide - + Immunofluorescence analysis of HeLa cells, using HINT1 antibody.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
HINT / HINT1 Antibody - Immunofluorescence analysis of HeLa cells, using HINT1 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
HINT / HINT1 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
HINT / HINT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µl/$386
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (Asn99) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
HINT / HINT1 Antibody - Western blot analysis of the lysates from HepG2 cells using HINT1 antibody.
Select
HINT / HINT1 Rabbit anti-Human Polyclonal (aa50-99) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25 of 41 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).