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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HIF3A / HIF3‑Alpha Antibody (Internal, DY550) LS‑C141071
HIF3-Alpha antibody LS-C141071 is a DY550-conjugated rabbit polyclonal antibody to HIF3-Alpha (HIF3A) from human and mouse. Validated for IP and WB.
Catalog
Size
Price
LS-C141071-100
100 µl
Unavailable

Popular HIF3A / HIF3-Alpha Products

HIF3A antibody LS-C31723 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-HIF3A antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B287 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Anti-HIF3A antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B714 concentration 5 ug/ml.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
IHC of paraffin-embedded Human lymph node tissue using anti-HIF3A mouse monoclonal antibody.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-HIF3A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

HIF3-Alpha antibody LS-C141071 is a DY550-conjugated rabbit polyclonal antibody to HIF3-Alpha (HIF3A) from human and mouse. Validated for IP and WB.
About HIF3A / HIF3-Alpha
Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. Isoform 4 has a dominant-negative function of inactivating HIF1A-mediated transcription. Q9Y2N7 NM_152795 NP_690008.2

HIF3A Antibody, BHLHe17 Antibody, HIF-3A Antibody, IPAS Antibody, HIF3-alpha-1 Antibody, Inhibitory PAS domain protein Antibody, PASD7 Antibody, HIF-3-alpha Antibody, HIF3-alpha Antibody, Member of PAS protein 7 Antibody, MOP7 Antibody


Specifications

Target
Human HIF3A / HIF3-Alpha
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
DyLight 550. Also available Unconjugated or conjugated with Biotin, DY650, DY488.
Purification
Purified IgG
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation (1:500 - 1:1000)
  • (applications tested for the base form of this product only)
Immunogen
A synthetic peptide made to an internal region of the human HIF-3 alpha (within residues 250-350). [Swiss-Prot# Q66K72]
Epitope
Internal
Specificity
HIF-3 alpha.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Detection of HIF-3 alpha. Lane 1: Cos7(-) control, Lane 2: Cos7-CoC12(+) Control.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of HIF-3 alpha. Lane 1: Cos7(-) control, Lane 2: Cos7-CoC12(+) Control. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of HIF-3 alpha. Lane 1: Cos7(-) control, Lane 2: Cos7-CoC12(+) Control.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of HIF-3 alpha. Lane 1: Cos7(-) control, Lane 2: Cos7-CoC12(+) Control. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of HIF-3 alpha. Lane 1: Cos7(-) control, Lane 2: Cos7-CoC12(+) Control.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of HIF-3 alpha. Lane 1: Cos7(-) control, Lane 2: Cos7-CoC12(+) Control. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of HIF-3 alpha. Lane 1: Cos7(-) control, Lane 2: Cos7-CoC12(+) Control.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of HIF-3 alpha. Lane 1: Cos7(-) control, Lane 2: Cos7-CoC12(+) Control. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/22/2018

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