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Anti-HIF2A / EPAS1 Antibody LS-C150132

Catalog Size Price
LS-C150132-25 25 µg (2 mg/ml) Unavailable
LS-C150132-100 100 µg (0.2 mg/ml) Unavailable

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Anti-HIF2A / EPAS1 Antibody LS-C150132
Goat Polyclonal (IgG) to Human HIF2A / EPAS1
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100% Guaranteed Publications (1)
Goat Polyclonal (IgG) to Human HIF2A / EPAS1
Human, Mouse, Rat
IHC - Frozen, Western blot


Human HIF2A / EPAS1
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC - Frozen (5 - 15 µg/ml)
  • Western blot (1 µg/ml)

Specificity and Use

HIF2A / EPAS1 antibody was raised against e. coli-derived recombinant mouse HIF2-alpha/EPAS1 Ser542-Thr874 Accession # AAH57870.
Detects human, mouse, and rat HIF2 alpha /EPAS1 in Western blots.
Western Blot, 1 µg/ml. Immunohistochemistry, 5-15 µg/ml, Immersion fixed frozen sections of mouse embryo (13-15 d. p. c.).


Lyophilized from PBS, pH 7.4, 5% trehalose
Sterile PBS.
Store at -20°C.
For research use only.

Publications (1)

Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes. Tojo Y, Sekine H, Hirano I, Pan X, Souma T, Tsujita T, Kawaguchi S, Takeda N, Takeda K, Fong GH, Dan T, Ichinose M, Miyata T, Yamamoto M, Suzuki N. Molecular and cellular biology. 2015 35:2658-72. (WB; Human) [Full Text Article] [PubMed:26012551] [PMC:PMC4524113]

About HIF2A / EPAS1

Q99814 NM_001430 NP_001421.2

EPAS1 Antibody, BHLHe73 Antibody, ECYT4 Antibody, HIF-1-alpha-like factor Antibody, HIF2-alpha Antibody, HIF2A Antibody, EPAS-1 Antibody, HIF-2-alpha Antibody, HIF-1alpha-like factor Antibody, MOP2 Antibody, Member of PAS protein 2 Antibody, PASD2 Antibody

Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier.

Western blot

Western blot
Detection of Human, Mouse, and Rat HIF-2 alpha/EPAS1 by Western Blot. Western blot shows lysates of MCF-7 human breast cancer cell line, bEnd.3 mouse endothelioma cell line, and PC-12 rat adrenal pheochromocytoma cell line untreated(-) or treated (+) with 150 uM CoCl2 for 16 hours. PVDF Membrane was probed with 1 ug/ml of Mouse HIF-2 alpha/EPAS1 Antigen Affinity-purified Polyclonal Antibody followed by HRP-conjugated Anti-Goat IgG Secondary Antibody. A specific band was detected for HIF-2 alpha/EPAS1 at approximately 120 kD (as indicated). This experiment was conducted under reducing conditions.

Requested From: 
Date Requested: 3/22/2018

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