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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HIF1A / HIF1 Alpha Antibody (aa432‑528) LS‑C124953
Antibody
HIF1 Alpha antibody LS-C124953 is an unconjugated mouse monoclonal antibody to human HIF1 Alpha (HIF1A). Validated for WB.
Catalog
Size
Price
LS-C124953-100
100 µl
Unavailable

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Product Description

HIF1 Alpha antibody LS-C124953 is an unconjugated mouse monoclonal antibody to human HIF1 Alpha (HIF1A). Validated for WB.
About HIF1A / HIF1 Alpha
Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Q16665 NM_001530 NP_001521.1

HIF1A Antibody, ARNT-interacting protein Antibody, ARNT interacting protein Antibody, BHLHe78 Antibody, HIF1 Alpha Antibody, Hypoxia-inducible factor1alpha Antibody, HIF-1A Antibody, HIF1 Antibody, MOP1 Antibody, Member of PAS superfamily 1 Antibody, PASD8 Antibody, HIF-1-alpha Antibody, HIF-1alpha Antibody, HIF1-ALPHA Antibody, Member of PAS protein 1 Antibody


Specifications

Target
Human HIF1A / HIF1 Alpha
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
Immunogen
Fusion protein containing amino acids 432-528 of human HIF-1 alpha.
Epitope
aa432-528
Specificity
Recognizes human HIF-1 alpha at ~120kD. Multiple bands may be observed at ~120kD representing post-translational modifications.
Usage
Suitable for use in Western blot: 1:500-1:1000.
Presentation
PBS, pH 7.4, 0.05% sodium azide
Storage
May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/25/2018

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