HFE2 / Hemojuvelin

hemochromatosis type 2 (juvenile)

HFE2 / Hemojuvelin is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.

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Products

Antibodies (102)

ELISA Kits (27)

Proteins (12)

Type

Competitive EIA (2)

Custom (3)

Development Kit (3)

Over-Expression Lysate (4)

Primary (102)

Recombinant (8)

Sandwich (17)

Sandwich CLIA (2)

Target

HFE2 / Hemojuvelin (141)

Reactivity

Human (112)

Mouse (34)

Rat (42)

Bovine (3)

Chimpanzee (3)

Gibbon (3)

Monkey (4)

Orangutan (3)

Pig (24)

Rabbit (3)

Application

IHC (10)

IHC-P (2)

WB (101)

Flo (7)

ELISA (14)

ICC (2)

Host

rabbit (61)

mouse (41)

Product Group

DevKit DuoPlus (3)

IHCPlus (1)

Isotype

IgG (27)

IgG1,k (8)

IgG2a,k (1)

IgG2b (6)

IgG2b,k (16)

Clonality

monoclonal mc (40)

polyclonal pc (62)

Clone

1C12 (1)

OTI3H2 (2)

OTI4E2 (2)

OTI8F4 (2)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (4)

96-Well Strip Plate (18)

Antibody Pair and Standard (3)

APC (8)

APC Conjugated (11)

Azide-free (2)

Biotin Conjugated (13)

Carrier-free (3)

Cy3 Conjugated (8)

Cy7 Conjugated (8)

FITC Conjugated (13)

HRP Conjugated (12)

PE Conjugated (11)

Unconjugated (26)

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Epitope

aa234-416 (16)

aa29-401 (10)

aa41-386 (8)

aa134-162 (7)

aa308-338 (7)

aa36-263 (6)

aa35-84 (4)

aa1-313 (1)

Publications

No (141)

Sample Type

Cell Culture Supernatants (8)

Cell Lysates (4)

Plasma (23)

Serum (23)

Tissue Homogenates (6)

Tag

Fc (1)

GST, N-terminus (1)

His (2)

His-GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (4)

Species

Human (10)

Source

293T Cells (2)

Baculovirus (1)

E. coli (4)

HEK 293 Cells (3)

Human (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

Select

IHC-plus™ HFE2 / Hemojuvelin Antibody (clone 1C12) LS-B7222

(4.0) Rating

Antibody:

HFE2 / Hemojuvelin Mouse anti-Human Monoclonal (1C12) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$440

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HFE2 / Hemojuvelin Antibody (aa308-338) LS-C166851

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa308-338) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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HFE2 / Hemojuvelin Antibody (PE) LS-C724880

Antibody:

HFE2 / Hemojuvelin Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$435; 200 µl/$531; 500 µl/$942; 1 ml/$1,112; 2 ml/$1,495; 5 ml/$2,801

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HFE2 / Hemojuvelin Antibody (aa234-416, FITC) LS-C303427

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa234-416) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$341; 200 µl/$397; 500 µl/$583; 1 ml/$715; 2 ml/$953; 5 ml/$1,628

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Human HFE2 / Hemojuvelin Protein (Recombinant His-T7) (aa29-401) - LS-G14602

Source:

E. coli

Tag:

His-T7

Molecular Weight:

43.5 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Human HFE2 / Hemojuvelin (Sandwich ELISA) ELISA Kit - LS-F31647

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

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HFE2 / Hemojuvelin Antibody (aa134-162) LS-C321938

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa134-162) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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HFE2 / Hemojuvelin Antibody (aa134-162, Biotin) LS-C236208

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa134-162) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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HFE2 / Hemojuvelin Antibody (aa134-162, FITC) LS-C236209

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa134-162) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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HFE2 / Hemojuvelin Antibody (aa134-162, PE) LS-C236213

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa134-162) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

HFE2 / Hemojuvelin Antibody (aa134-162, Azide-free, HRP) LS-C249185

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa134-162) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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HFE2 / Hemojuvelin Antibody (aa134-162, APC) LS-C236207

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa134-162) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• HRP, Azide-free
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • HRP, Azide-free
  • APC

Select

HFE2 / Hemojuvelin Antibody (aa134-162) LS-C166852

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa134-162) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

HFE2 / Hemojuvelin Antibody LS-C341585

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

HFE2 / Hemojuvelin Antibody LS-C333998

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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HFE2 / Hemojuvelin Antibody (aa308-338) LS-C321936

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa308-338) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

HFE2 / Hemojuvelin Antibody (aa308-338, Biotin) LS-C236203

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa308-338) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

HFE2 / Hemojuvelin Antibody (aa308-338, FITC) LS-C236204

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa308-338) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

HFE2 / Hemojuvelin Antibody (aa308-338, Azide-free, HRP) LS-C249184

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa308-338) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

HFE2 / Hemojuvelin Antibody (aa308-338, APC) LS-C236202

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa308-338) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

HFE2 / Hemojuvelin Antibody (aa308-338, PE) LS-C236205

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa308-338) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

HFE2 / Hemojuvelin Antibody LS-C779461

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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HFE2 / Hemojuvelin Antibody LS-C663700

Antibody:

HFE2 / Hemojuvelin Mouse anti-Human Monoclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$323; 200 µl/$371; 500 µl/$531; 1 ml/$617; 2 ml/$850; 5 ml/$1,401

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HFE2 / Hemojuvelin Antibody (aa29-401, Biotin) LS-C421443

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa29-401) (Biotin) Antibody

Reactivity:

Human

Applications:

ICC, WB

Format:

Biotin Conjugated

Price:

100 µl/$313

Select

HFE2 / Hemojuvelin Antibody (aa29-401, FITC) LS-C421442

Antibody:

HFE2 / Hemojuvelin Rabbit anti-Human Polyclonal (aa29-401) (FITC) Antibody

Reactivity:

Human

Applications:

ICC, WB

Format:

FITC Conjugated

Price:

100 µl/$322

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