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Anti-HES1 / HES-1 Antibody (aa24-35) IHC-plus™ LS-B2211

Note: This antibody replaces LS-C24204

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml Unavailable

Most Popular HES1 / HES-1 Antibodies

Anti-HES1 / HES-1 Antibody (aa24-35) IHC-plus™ LS-B2211
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Rabbit, Xenopus, Zebrafish
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-HES1 / HES-1 Antibody (C-Terminus) LS-C134938
Rabbit Polyclonal to Rat HES1 / HES-1
Rat, Human, Mouse, Bovine, Pig
Western blot
Unconjugated
Western blot Image
Anti-HES1 / HES-1 Antibody (N-Terminus) IHC-plus™ LS-B6364
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Rabbit, Xenopus, Zebrafish
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human HES1 / HES-1
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Rabbit, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750, PE.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • IHC - Frozen
  • Immunofluorescence
  • Western blot (1:200 - 1:1000)
  • (applications tested for the base form of this product only)

Specificity and Use

HES1 / HES-1 antibody was raised against synthetic peptide corresponding to aa24-35 (TPDKPKTASEH) OF HES1. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Bovine, Horse, Rabbit, Xenopus, Salmon, Stickleback, Pufferfish, Zebrafish (100%); Newt, Smelt (91%); Chicken (82%).
aa24-35
Recognizes human HES-1 (Hairy family).
Immunohistochemistry: LS-B2211 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2211 was determined to be 5 ug/ml. Positive control: Human neural stem cells, Raji cell lysate.

Packaging

PBS, pH 7.2. No preservative added.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About HES1 / HES-1

Q14469 NM_005524 NP_005515.1

HES1 Antibody, BHLHb39 Antibody, HHL Antibody, HL Antibody, Hairy and enhancer of split 1 Antibody, Hairy homolog Antibody, HRY Antibody, Hairy homolog (Drosophila) Antibody, Transcription factor HES-1 Antibody, Hairy-like protein Antibody, HES-1 Antibody

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity).

Immunohistochemistry

Immunohistochemistry
Anti-HES1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2211 concentration 5 ug/ml.
 

Requested From: 
Date Requested: 3/29/2017

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