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HDAC9
histone deacetylase 9
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter.
| Gene Name: | histone deacetylase 9 |
| Family/Subfamily: | Histone Deacetylase , not assigned-Histone Deacetylase |
| Synonyms: | HDAC9, HD7, HD9, HDAC, HDAC7B, HDAC9B, HDAC9FL, KIAA0744, HD7b, HDRP, Histone deacetylase 7B, Histone deacetylase 9, MITR |
| Target Sequences: | NM_014707 NP_055522.1 Q9UKV0 |
Publications (2)
1
Mirk/dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation. Deng X, Ewton DZ, Mercer SE, Friedman E. The Journal of biological chemistry. 2005 280:4894-905.
[PubMed:15546868]
Related Antibodies: LS-C96661.
2
Specific control of pancreatic endocrine - and -cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9. Lenoir O, Flosseau K, Ma FX, Blondeau B, Mai A, Bassel-Duby R, Ravassard P, Olson EN, Haumaitre C, Scharfmann R. Diabetes. 2011 60:2861-71.
[PubMed:21953612]
[PMC:PMC3198089]
Related Antibodies: LS-C96662.
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HDAC9 Rabbit anti-Human Polyclonal (aa503-533) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
293T Cells
Myc-DDK (Flag)
117 kDa
20 µg/$215
HDAC9 Rabbit anti-Human Polyclonal (aa2-32) Antibody
Human
IF, IHC, IHC-P, IP, WB
Unconjugated
400 µl/$393
HDAC9 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
HDAC9 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
HDAC9 Rabbit anti-Human Polyclonal (aa1017-1066) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
HDAC9 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
HDAC9 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
HDAC9 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
HDAC9 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
HDAC9 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
HDAC9 Rabbit anti-Human Polyclonal (aa2-32) Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
200 µl/$734
HDAC9 Rabbit anti-Human Polyclonal (aa2-32) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, IP, WB
Biotin Conjugated
200 µl/$952
HDAC9 Rabbit anti-Human Polyclonal (aa2-32) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, IP, WB
FITC Conjugated
200 µl/$952
HDAC9 Rabbit anti-Human Polyclonal (aa2-32) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, IP, WB
HRP Conjugated, Azide-free
200 µl/$952
HDAC9 Rabbit anti-Human Polyclonal (aa2-32) (APC) Antibody
Human
ELISA, ICC, IF, IHC, IP, WB
APC Conjugated
200 µl/$952
HDAC9 Rabbit anti-Human Polyclonal (aa2-32) (PE) Antibody
Human
ELISA, ICC, IF, IHC, IP, WB
PE Conjugated
200 µl/$952
HDAC9 Rabbit anti-Human Polyclonal (980-1060 aa, C-terminal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HDAC9 Rabbit anti-Human Polyclonal (Pro1047) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
HDAC9 Mouse anti-Human Monoclonal (aa181-460) (OTI7G2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
HDAC9 Mouse anti-Human Monoclonal (aa181-460) (Carrier-free) (OTI7G2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HDAC9 Rabbit anti-Human Polyclonal (aa503-533) Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
200 µl/$734
HDAC9 Rabbit anti-Human Polyclonal (aa503-533) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, IP, WB
HRP Conjugated, Azide-free
200 µl/$952
HDAC9 Mouse anti-Human Monoclonal (aa181-460) (OTI6E2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
HDAC9 Mouse anti-Human Monoclonal (aa181-460) (OTI2A7) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
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