HDAC8

histone deacetylase 8

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

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Products

Antibodies (74)

Proteins (11)

ELISA Kits (7)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (4)

Over-Expression Lysate (4)

Primary (74)

Recombinant (7)

Sandwich (1)

Target

HDAC8 (92)

Reactivity

Human (77)

Mouse (27)

Rat (26)

Bat (1)

Bovine (7)

Chicken (1)

Chimpanzee (6)

Dog (4)

Gibbon (3)

Guinea pig (1)

Horse (3)

Monkey (8)

Pig (2)

Rabbit (7)

Xenopus (1)

Zebrafish (1)

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Application

IHC (37)

IHC-P (16)

WB (62)

ELISA (31)

ICC (2)

IF (8)

IP (4)

Peptide-ELISA (4)

Host

rabbit (55)

mouse (19)

Product Group

IHCPlus (1)

Isotype

IgG (39)

IgG1 (10)

IgG2a,k (1)

IgG2b (2)

IgG2b,k (6)

Clonality

monoclonal mc (19)

polyclonal pc (55)

Clone

10D56 (1)

2F4 (1)

OTI1A4 (2)

OTI1B2 (2)

OTI3F6 (2)

OTI5F7 (2)

OTI9F2 (2)

OTI9H8 (2)

Format

96-Well Microplate (2)

96-Well Strip Plate (5)

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Azide-free (2)

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Carrier-free (6)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (3)

Unconjugated (47)

Epitope

aa1-243 (12)

aa1-30 (7)

N-Terminus (6)

aa1-377 (6)

pSer39 (6)

C-Terminus (5)

20-100 aa (2)

Lys33 (1)

aa1-378 (1)

aa18-33 (1)

aa305-377 (1)

aa5-54 (1)

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Publications

No (92)

Sample Type

Adherent Cell Cultures (2)

Plasma (1)

Serum (1)

Tissue Homogenates (1)

Tag

GST (2)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

His-SUMO (1)

Myc-DDK (Flag) (4)

Species

Human (8)

Mouse (1)

Source

293T Cells (2)

Baculovirus (2)

E. coli (2)

HEK 293 Cells (2)

Sf9 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (2)

Select

HDAC8 Antibody (C-Terminus) LS-B967

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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HDAC8 Antibody (C-Terminus, HRP) LS-C431428

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP

• Unconjugated
• HRP

Select

HDAC8 Antibody (aa305-377) LS-C7418

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (aa305-377) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$947

Select

HDAC8 Antibody (clone 2F4) LS-C139403

Antibody:

HDAC8 Mouse anti-Human Monoclonal (2F4) Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

HDAC8 Antibody (aa1-377) LS-C375897

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (aa1-377) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

HDAC8 Antibody (phospho-Ser39) LS-C354196

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (pSer39) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$315

Select

HDAC8 Antibody (phospho-Ser39) LS-C801230

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (pSer39) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

HDAC8 Antibody LS-C801669

Antibody:

HDAC8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

HDAC8 Antibody (aa1-377) LS-C375898

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (aa1-377) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

HDAC8 Antibody (aa1-377) LS-C369774

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (aa1-377) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

HDAC8 Antibody LS-C404045

Antibody:

HDAC8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

HDAC8 Antibody (phospho-Ser39) LS-C199046

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (pSer39) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

HDAC8 Antibody (C-Terminus) LS-C209400

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$567

Select

HDAC8 Antibody (N-Terminus) LS-C209402

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$567

Select

HDAC8 Antibody (aa1-30) LS-C327520

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

HDAC8 Antibody (aa1-30, FITC) LS-C244611

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

• Unconjugated
• FITC

• Unconjugated
• FITC

Select

HDAC8 Antibody (aa18-33) LS-C312748

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (aa18-33) Antibody

Reactivity:

Mouse, Guinea pig, Rat, Pig, Bat, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

HDAC8 Antibody (20-100 aa) LS-C380726

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (20-100 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

HDAC8 Antibody (Biotin) LS-C526439

Antibody:

HDAC8 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

HDAC8 Antibody (FITC) LS-C536438

Antibody:

HDAC8 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

HDAC8 Antibody (aa1-378, clone 10D56, Azide-free) LS-C183675

Antibody:

HDAC8 Mouse anti-Human Monoclonal (aa1-378) (Azide-free) (10D56) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, WB

Format:

Unconjugated, Azide-free

Price:

100 µg/$705

Select

HDAC8 Antibody (APC) LS-C517085

Antibody:

HDAC8 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

APC Conjugated

Price:

100 µl/$904

Select

HDAC8 Antibody (PE) LS-C654614

Antibody:

HDAC8 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

PE Conjugated

Price:

100 µl/$904

• Biotin
• FITC
• Unconjugated, Azide-free
• APC
• PE

• Biotin
• FITC
• Unconjugated, Azide-free
• More...
  • APC
  • PE

Select

HDAC8 Antibody (20-100 aa) LS-C383907

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (20-100 aa) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

HDAC8 Antibody (p39) LS-C826261

Antibody:

HDAC8 Rabbit anti-Human Polyclonal (p39) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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