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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HDAC6 Antibody (N‑Terminus) LS‑C48563
Antibody
HDAC6 antibody LS-C48563 is an unconjugated rabbit polyclonal antibody to HDAC6 from human, mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C48563-30
30 µg
Unavailable
LS-C48563-100
100 µg (0.5 mg/ml)
Unavailable

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Product Description

HDAC6 antibody LS-C48563 is an unconjugated rabbit polyclonal antibody to HDAC6 from human, mouse and rat. Validated for IHC and WB.
About HDAC6
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Q9UBN7 NM_006044 NP_006035.2

HDAC6 Antibody, Histone deacetylase 6 Antibody, HD6 Antibody, KIAA0901 Antibody, JM21 Antibody


Specifications

Target
Mouse HDAC6
Host
Rabbit
Reactivity
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC (20 µg/ml)
  • Western blot (0.5 - 4 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
Immunogen
HDAC6 antibody was raised against synthetic peptide mapping to the N-terminus of mouse HDAC-6.
Epitope
N-Terminus
Specificity
The antibody detects ~134 kD HDAC-6. Mouse small intestine tissue lysate can be used as a positive control. The antibody does not cross-react with other HDAC proteins including HDAC1, 2, 3, 4, 5, 7, and 8.
Presentation
PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.01% Thimerosal.
Storage
Short term: -20°C; Long term: -70°C; Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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