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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HDAC5 Antibody (phospho‑Ser498) LS‑C190888
Antibody
HDAC5 antibody LS-C190888 is an unconjugated rabbit polyclonal antibody to HDAC5 from human, mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C190888-50
50 µg
Unavailable

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Product Description

HDAC5 antibody LS-C190888 is an unconjugated rabbit polyclonal antibody to HDAC5 from human, mouse and rat. Validated for IHC and WB.
About HDAC5
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. Q9UQL6 NM_005474 NP_005465.2

HDAC5 Antibody, Antigen NY-CO-9 Antibody, Histone deacetylase 5 Antibody, NY-CO-9 Antibody, HD5 Antibody, KIAA0600 Antibody


Specifications

Target
Human HDAC5
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:500 - 1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
HDAC5 antibody was raised against synthetic phosphopeptide corresponding to human HDAC5 around the phosphorylation site of serine 498 (T-Q-SP-S-P).
Epitope
pSer498
Specificity
Human HDAC-5, phosphorylated at Ser498. Species Crossreactivity: mouse and rat.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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