The Immunohistochemistry Antibody Company
|Human, Mouse, Rat, Chicken (tested or 100% immunogen sequence identity)|
|HDAC3 antibody was raised against synthetic peptide corresponding to the C-terminus of human HDAC-3.|
|The antibody detects the 49 kD HDAC3. It does not cross-react with other HDAC proteins including HDAC1, 2, 4, 5, 6, 7, and 8. Jurkat cell lysate can be used as a positive control. Blocking peptide is also available.|
|PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.01% Thimerosal.|
|Long term: -70°C; Short term: -20°C|
|For research use only.|
HDAC3 Antibody, RPD3 Antibody, SMAP45 Antibody, HD3 Antibody, Histone deacetylase 3 Antibody, RPD3-2 AntibodyResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.