LSBio The Immunohistochemistry Antibody Company
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-HAVCR1 / KIM-1 Antibody (clone RMT1-10, RPE) LS-C187572


Wt. Vol. Conc. Price
- 100 tst - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-C187569 Unconjugated, Low Endotoxin
LS-C187571 Unconjugated
LS-C187570 FITC Conjugated

Most Popular HAVCR1 / KIM-1 Antibodies

Anti-HAVCR1 / KIM-1 Antibody (aa200-300) IHC-plus™ LS-B2031
Rabbit Polyclonal (IgG) to Human HAVCR1 / KIM-1
Human, Mouse
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-HAVCR1 / KIM-1 Antibody (N-Terminus) IHC-plus™ LS-B2103
Rabbit Polyclonal to Human HAVCR1 / KIM-1
Human, Mouse
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-HAVCR1 / KIM-1 Antibody (Internal) IHC-plus™ LS-B2463
Rabbit Polyclonal to Human HAVCR1 / KIM-1
Human, Mouse, Rat
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone RMT1-10] (IgG2a) to Mouse HAVCR1 / KIM-1
Immunofluorescence, Flow Cytometry, ELISA (applications tested for the base form of this product only)
RPE Conjugated


Mouse HAVCR1 / KIM-1
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [RMT1-10]
R. Phycoerythrin
Protein G purified


  • Immunofluorescence
  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

HAVCR1 / KIM-1 antibody was raised against full-length mouse Tim-1-Ig, containing both the IgV and mucin domains of Tim-1.
Clone RMT1-10 specifically recognizes mouse Tim-1 (T-cell immunoglobulin mucin 1), a cell surface glycoprotein and member of the immunoglobulin superfamily, which was first identified as the hepatitis A virus cellular receptor (HAVCR), and is highly expressed in the liver (isoform Tim-1a) and the kidneys (isoform Tim-1b). Tim-1 is highly expressed by activated CD4+ T cells, and acts as a positive/negative co-stimulatory molecule of T cell proliferation, cytokine production and tolerance abrogation, and is the receptor for Tim-4, expressed on APCs. Tim-1 expression is greater on Th2 than Th1 cells, and studies have shown that interaction between Tim-1 on Th2 cells and Tim-4 on dendritic cells (DCs), enhances Th2 cell function, and have implicated Tim-1 as a critical player in the development of atopic disease, and in particular airway hypersensitivity. Polymorphic forms of Tim-1 are associated with increased susceptibility to asthma, eczema and Rheumatoid arthritis. Clone RMT1-10 has been shown to promote Th2 responses, and inhibit antigen-specific T cell proliferation, in contrast to the agonistic function of many Tim-1 antibodies see for details. Clone RMT1-10 has been shown to reduce the severity of EAE (experimental autoimmune encephalomyelitis) and delay disease onset, in mice studies see for details.
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.


PBS, 0.09% sodium azide, 1% BSA, 5% sucrose
100 tst 1 ml sterile distilled water
Store at +4°C. Do not freeze. Protect from light.
For research use only.

About HAVCR1 / KIM-1

Q96D42 NM_012206 NP_036338.2

HAVCR1 Antibody, HAVCR-1 Antibody, KIM-1 Antibody, Kidney injury molecule 1 Antibody, KIM1 Antibody, T-cell membrane protein 1 Antibody, TIM1 Antibody, TIMD1 Antibody, TIM-1 Antibody, HAVCR Antibody, TIMD-1 Antibody

Hepatitis A Virus Cellular Receptor 1 (HAVCR1) is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. HAVCR1 may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals.

Flow Cytometry

Flow Cytometry
TIM-1 transfected NRK cells stained with Rat anti-Mouse TIM-1. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/24/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number