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HAUS3 / C4orf15 is a component of the HAUS augmin-like protein complex, which plays a key role in cytokinesis and mitosis. Disruption of the encoded protein causes mitotic defects resulting from fragmentation of centrosomes and microtubule destabilization. This gene shares its 5' exons with some transcripts from overlapping GeneID: 353497, which encodes a DNA polymerase. Alternative splicing results in multiple transcript variants.
Gene Name: | HAUS augmin-like complex, subunit 3 |
Synonyms: | HAUS3, C4orf15, Dgt3, IT1 |
Target Sequences: | AF040964 AAB97010.1 Q68CZ6 |
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