Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
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immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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IHC, IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Rabbit Polyclonal to Human Hamartin / TSC1
Human
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Details
Human Hamartin / TSC1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified
Applications
IHC
IHC - Paraffin (1:10 - 1:50)
Immunofluorescence (1:10 - 1:50)
Western blot (1:1000)
Specificity and Use
aa401-430
This Hamartin (TSC1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the Central region of human Hamartin (TSC1).
Packaging
PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors.
Hamartin (TSC1) Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.This data demonstrates the use of Hamartin (TSC1) Antibody for immunohistochemistry.
Immunofluorescence
Confocal immunofluorescence of Hamartin (TSC1) Antibody with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Western blot
TSC1 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The TSC1 antibody detected the TSC1 protein (arrow).