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H2AFY / MACROH2A1

H2A histone family, member Y

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces a hypoacetylated state of chromatin. In addition, isoform 1, but not isoform 2, binds ADP-ribose and O-acetyl-ADP-ribose, and may be involved in ADP-ribose-mediated chromatin modulation.

Gene Name: H2A histone family, member Y
Synonyms: H2AFY, Core histone macro-H2A.1, Histone macroH2A1.1, H2A histone family, member Y, H2A.y, Histone H2A.y, MACROH2A1.1, MacroH2A1.2, H2AF12M, Histone macroH2A1.2, MACROH2A1, Histone macroH2A1, MH2A1
Target Sequences: NM_004893 NP_004884.1 O75367

☰ Filters
Antibodies (31)
Proteins (8)
Over-Expression Lysate (4)
Primary (31)
Recombinant (4)
H2AFY / MACROH2A1 (39)
Human (31)
Mouse (15)
Rat (15)
Bat (6)
Bovine (9)
Chicken (6)
Chimpanzee (9)
Dog (6)
Gibbon (6)
Guinea pig (6)
Horse (9)
Monkey (10)
Pig (14)
Rabbit (6)
Xenopus (3)
Zebrafish (3)
IHC (12)
IHC-P (7)
WB (30)
ELISA (2)
ICC (1)
IF (4)
Peptide-ELISA (1)
rabbit (28)
rabbit-new zealand white (3)
Product Group
IHCPlus (1)
IgG (19)
polyclonal pc (31)
APC (1)
APC Conjugated (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (15)
aa109-369 (8)
N-Terminus (4)
aa144-193 (4)
aa36-85 (4)
No (39)
GST (1)
His, N-Terminal (1)
His-GST (1)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
H2AFY / MACROH2A1 Antibody - Immunohistochemical analysis of MacroH2A1 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
H2AFY / MACROH2A1 Antibody - Anti-H2AFY / MACROH2A1 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa144-193) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
H2AFY / MACROH2A1 Antibody - Anti-H2AFY / MACROH2A1 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa144-193) (HRP) Antibody
Mouse, Bovine, Rat, Horse, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
H2AFY / MACROH2A1 Antibody - Anti-H2AFY / MACROH2A1 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa144-193) (Biotin) Antibody
Mouse, Bovine, Rat, Horse, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
H2AFY / MACROH2A1 Antibody - Anti-H2AFY / MACROH2A1 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa144-193) (FITC) Antibody
Mouse, Bovine, Rat, Horse, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
H2AFY / MACROH2A1 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
H2AFY / MACROH2A1 Antibody - Immunohistochemistry of paraffin-embedded human thyroid tissue at dilution 1:100
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
H2AFY / MACROH2A1 Antibody - Immunohistochemistry of paraffin-embedded human thyroid tissue at dilution 1:100
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, WB
Unconjugated
100 µl/$688
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H2AFY / MACROH2A1 Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$393
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H2AFY / MACROH2A1 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
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H2AFY / MACROH2A1 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
H2AFY / MACROH2A1 Antibody - Western blot of recombinant H2AFY / MACROH2A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa109-369) Antibody
Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
H2AFY / MACROH2A1 Antibody - Western blot of recombinant H2AFY / MACROH2A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa109-369) (HRP) Antibody
Pig, Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
H2AFY / MACROH2A1 Antibody - Western blot of recombinant H2AFY / MACROH2A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa109-369) (Biotin) Antibody
Pig, Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
H2AFY / MACROH2A1 Antibody - Western blot of recombinant H2AFY / MACROH2A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa109-369) (FITC) Antibody
Pig, Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
H2AFY / MACROH2A1 Antibody - Western blot of recombinant H2AFY / MACROH2A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa109-369) (PE) Antibody
Pig, Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
H2AFY / MACROH2A1 Antibody - Western blot of recombinant H2AFY / MACROH2A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa109-369) (Cy3) Antibody
Pig, Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
H2AFY / MACROH2A1 Antibody - Western blot of recombinant H2AFY / MACROH2A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa109-369) (APC, Cy7) Antibody
Pig, Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
H2AFY / MACROH2A1 Antibody - Western blot of recombinant H2AFY / MACROH2A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa109-369) (APC) Antibody
Pig, Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
H2AFY / MACROH2A1 Antibody - H2AFY antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
H2AFY / MACROH2A1 Antibody - H2AFY antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
WB
Unconjugated
100 µl/$424
H2AFY / MACROH2A1 Antibody - Anti-H2AFY rabbit polyclonal antibody at 1:500 dilution. Lane A: HeLa Whole Cell Lysate. Lane B: HepG2 Whole Cell Lysate. Lane C: MCF7 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 40 kDa. Observed band size: 40 kDa.
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H2AFY / MACROH2A1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
WB
Unconjugated, Preservative Free
100 µl/$412
Viewing 1-25 of 39 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).