Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 34-1-2S] (IgG2a) to Mouse H-2Kd + H-2Dd
Flow Cytometry, Cytotoxic Assay
Mouse H-2Kd + H-2Dd
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [34-1-2S]
Protein G purified
Flow Cytometry (0.5 µg/10E6 cells)
Cytotoxic Assay (1:40 - 1:160)
IHC - Paraffin
Specificity and Use
Anti H-2KdDd mAb reacts with both H-2Kd and H-2Dd products. The antibody also cross reacts with Kbsrpq. This K-D cross reaction indicates the presence of shared specificities between the two separate H-2 regions
PBS, 0.02% sodium azide.
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.