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Anti-GZMB / Granzyme B Antibody (N-Terminus) IHC-plus™ LS-B2783

Note: This antibody replaces LS-C50550


Wt. Vol. Conc. Price
- 50 µl - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular GZMB / Granzyme B Antibodies

Anti-GZMB / Granzyme B Antibody (clone GB11) LS-C44295
Mouse Monoclonal [clone GB11] (IgG1) to Human GZMB / Granzyme B
Human, Monkey, Rhesus monkey
IHC - Frozen, Immunoprecipitation, Flow Cytometry, ELISA
Anti-GZMB / Granzyme B Antibody (N-Terminus) IHC-plus™ LS-B2783
Rabbit Polyclonal to Human GZMB / Granzyme B
Human, Mouse, Rat
IHC - Paraffin
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human GZMB / Granzyme B
Human, Mouse, Rat
IHC - Paraffin


Human GZMB / Granzyme B
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Immunoaffinity purified


IHC - Paraffin (1:100)

Specificity and Use

GZMB / Granzyme B antibody was raised against a synthetic peptide from N-terminus of human Granzyme B.
Immunohistochemistry: LS-B2783 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2783 was determined to be 10 ug/ml.


10 mM PBS, pH 7.4, BSA, sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About GZMB / Granzyme B

P10144 NM_004131 NP_004122.2

GZMB Antibody, CCPI Antibody, CGL-1 Antibody, Cathepsin G-like 1 Antibody, CSP-B Antibody, CTLA-1 Antibody, CTLA1 Antibody, CGL1 Antibody, CSPB Antibody, Fragmentin 2 Antibody, GRB Antibody, HLP Antibody, Human lymphocyte protein Antibody, Fragmentin-2 Antibody, SECT Antibody, Lymphocyte protease Antibody, T-cell serine protease 1-3E Antibody, C11 Antibody, CTSGL1 Antibody, Cytotoxic serine protease B Antibody, Granzyme B Antibody, Granzyme-2 Antibody

This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.


Anti-GZMB / Granzyme B antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2783 concentration 10 ug/ml.

Requested From: United States
Date Requested: 10/24/2016

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